Tinnitus and Brain Reorganization
Tinnitus is an auditory sensation in the absence of any sound source outside the body. These perveived sounds may be described as whistles, ringing, hissing, buzzing. These sounds may be associated with some hearingloss.There appear too be too many neurons,dedicated to the same frequency. The reorganization of the auditory cortex would be the cause of tinnitus, and recent scientific articles, have shown that the degree of this reorganization was correlated with the intensity of the tinnitus.
Tinnitus and Brain Reorganization
What researches are considering, is a way to reverse these changes, and so permanently eliminate the tinnitus. Electrical stimulation
Scientists at the University of Dallas, Texas and MicroTransponder Inc.. then wanted to try to reorganize the brain permanently, in order to learn to function normally experience they had attempted on an animal model: the rat.
Scheme of the experiment. Rats were subjected to intense noise (exposure to intense noise) to cause tinnitus (tinnitus). These rats were then subjected to a frequency (tone, blue), to stimulation of the vagus nerve (vagus nerve stimulation, in red) or both simultaneously. Only the third solution is effective in eliminating tinnitus (no tinnitus) and restore normal neuronal activity. © Nature
Use the plasticity of the brain
Tinnitus and Brain Reorganization
The researchers first tried to change the organization of auditory cortex by means of an inventive strategy: let them hear a dial tone sounds clear (frequency controlled), while stimulating the vagus nerve. It connects the head to the abdomen and its stimulation causes the release of neurotransmitters ( acetylcholine , norepinephrine) that promote neuronal plasticity. In short, their goal was to increase the number of neurons responding to the same frequency in order to reduce, by simply clearing the number of those involved in the response to the frequency of tinnitus, and it worked. After two days of intensive treatment (three hundred daily stimulations of the vagus nerve and broadcast simultaneously to 19 kHz sound), rats tested on average received a 70% increase in the number of neurons responding to a sound of 19 kHz while the neurons dedicated to the frequency of 4 kHz were fewer than before treatment.
Tinnitus and Brain Reorganization
The researchers conducted the same experiment in rats suffering from tinnitus, which have the distinction of being unable to detect a stop of his at a frequency close to that of their tinnitus, but to detect breaks in the frequencies above and below . By stimulating the vagus nerve simultaneously with the emission of sounds at different frequencies, except that of the tinnitus, again, it's a success. After only ten days of therapy , the effect is already visible (rats detect the break of his), and is still seen more than three months after the end of therapy. And for good reason, the number of neurons assigned to the frequency of the tinnitus returned to normal.
According to Michael Kilgard, one of the authors of the article in Nature , "the key is that, unlike previous treatments, we do not mask the tinnitus, we do not hide. We eliminate the source of tinnitus. "Techniques involving stimulation of the vagus nerve are also used for the treatment of depression and of epilepsy . Regarding tinnitus, a first pilot study on humans should begin shortly.
The extraordinary lengths science will go to, in their endeavors to solve a tormenting and prevalent problem, which can be solved with holistic medicine. Hard to tell how they identified tinnitus in rats. Science always attacks the body from the outside, with crude medicine, or lopping off vital parts, rather than resolving the problem, by treating from the inside to the outer.
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